The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH)

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4674-85. doi: 10.1016/j.bmcl.2011.06.096. Epub 2011 Jun 28.

Abstract

A summary of the discovery and advancement of inhibitors of fatty acid amide hydrolase (FAAH) is presented.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Amidohydrolases / antagonists & inhibitors*
  • Animals
  • Drug Discovery*
  • Enzyme Inhibitors / chemical synthesis
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Humans
  • Molecular Structure
  • Stereoisomerism
  • Structure-Activity Relationship

Substances

  • Enzyme Inhibitors
  • Amidohydrolases
  • fatty-acid amide hydrolase