High-frequency and low-frequency chest compression: effects on lung water secretion, mucus transport, heart rate, and blood pressure using a trapezoidal source pressure waveform

IEEE Trans Biomed Eng. 2012 Jan;59(1):106-14. doi: 10.1109/TBME.2011.2161608. Epub 2011 Jul 18.

Abstract

High-frequency chest compression (HFCC), using an appropriate source (pump) waveform for frequencies at or above 3 Hz, can enhance pulmonary clearance for patients with cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). Using a trapezoidal HFCC source pressure waveform, secretion of water from epithelial tissue and transport of mucus through lung airways can be enhanced for patients with CF and COPD. At frequencies below 3 Hz, low-frequency chest compression (LFCC) appears to have a significant impact on the cardiovascular system. For a trapezoidal source pressure waveform at frequencies close to 1 Hz, LFCC produces amplitude or intensity variations in various components of the electrocardiogram time-domain waveform, produces changes at very low frequencies associated with the electrocardiogram frequency spectra (indicating enhanced parasympathetic nervous system activity), and promotes a form of heart rate synchronization. It appears that LFCC can also provide additional cardiovascular benefits by reducing peak and average systolic and diastolic blood pressure for patients with hypertension.

MeSH terms

  • Biological Transport, Active
  • Blood Pressure*
  • Body Water / metabolism*
  • Chest Wall Oscillation / methods*
  • Computer Simulation
  • Cystic Fibrosis / physiopathology
  • Cystic Fibrosis / rehabilitation
  • Heart Rate*
  • Humans
  • Lung / physiopathology*
  • Models, Biological*
  • Mucus / metabolism*
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Disease, Chronic Obstructive / rehabilitation
  • Therapy, Computer-Assisted / methods