The human alkaline phosphatases: what we know and what we don't know

Clin Chim Acta. 1990 Jan 15;186(2):133-50. doi: 10.1016/0009-8981(90)90031-m.

Abstract

A review of the human alkaline phosphatases dealing specifically with (1) the gene loci, (2) characterization and discrimination of the various enzymes, (3) polymorphism at the enzyme level, (4) cDNA and gene structures, (5) membrane binding, (6) the carbohydrate moieties, (7) hypophosphatasia, (8) alkaline phosphatases in malignancies, (9) function.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Alkaline Phosphatase / genetics*
  • Alkaline Phosphatase / physiology
  • Carbohydrates / analysis
  • Cell Membrane / metabolism
  • Chromosome Mapping
  • DNA / analysis
  • Genes
  • Humans
  • Hypophosphatasia / genetics*
  • Isoenzymes / genetics*
  • Isoenzymes / physiology
  • Neoplasms / enzymology*
  • Polymorphism, Genetic / physiology*
  • Sequence Homology, Nucleic Acid

Substances

  • Carbohydrates
  • Isoenzymes
  • DNA
  • Alkaline Phosphatase