Vascularity of nongynecological leiomyosarcoma depends on colony-stimulating factor 1 but not on vascular endothelial growth factor

Am J Pathol. 2011 Oct;179(4):1591-3. doi: 10.1016/j.ajpath.2011.07.008. Epub 2011 Aug 10.

Abstract

This Commentary highlights the article by Espinosa et al (in this issue), expounding on the rationale for CSF-1-targeted therapies in non-gynecological leiomyosarcomas.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Animals
  • Female
  • Humans
  • Leiomyosarcoma / blood supply*
  • Leiomyosarcoma / pathology*
  • Macrophage Colony-Stimulating Factor / metabolism*
  • Male
  • Neovascularization, Pathologic / metabolism*

Substances

  • Macrophage Colony-Stimulating Factor