Acquisition of the novel ABL kinase domain mutation T315L in a relapsed Philadelphia-positive acute lymphoblastic leukemia patient

Leuk Res. 2012 Jan;36(1):e20-1. doi: 10.1016/j.leukres.2011.08.011. Epub 2011 Sep 6.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Amino Acid Substitution / physiology
  • Base Sequence
  • Catalytic Domain / genetics
  • Fusion Proteins, bcr-abl / chemistry
  • Fusion Proteins, bcr-abl / genetics*
  • Humans
  • Karyotype
  • Leucine / genetics
  • Male
  • Middle Aged
  • Mutation, Missense*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Recurrence
  • Threonine / genetics

Substances

  • Threonine
  • Fusion Proteins, bcr-abl
  • Leucine