The introduction of chlorpromazine in Belgium and the Netherlands (1951-1968); tango between old and new treatment features

Stud Hist Philos Biol Biomed Sci. 2011 Dec;42(4):443-52. doi: 10.1016/j.shpsc.2011.05.003. Epub 2011 Jun 22.

Abstract

The introduction of chlorpromazine in Belgium and the Netherlands demonstrates an intriguing tango between old and new treatments. Chlorpromazine, marketed by the French company Rhône Poulenc entered psychiatry as an adjunct to existing therapies. Instead of promoting chlorpromazine as a revolutionary therapy, we see early efforts to market Largactil as a supplement to the armoury of psychiatric treatments. These marketing efforts matched the idiosyncrasies of national and local styles and cultures. Despite continuities with earlier therapeutic developments, we support the notion of a therapeutic revolution. In the early sixties supply and demand provoked a turn towards more standardized therapeutic regimes.

Publication types

  • Historical Article

MeSH terms

  • Belgium
  • Chlorpromazine / history*
  • Chlorpromazine / therapeutic use
  • Culture*
  • Drug Industry / history*
  • France
  • History, 20th Century
  • Humans
  • Marketing / history*
  • Mental Disorders / drug therapy
  • Mental Disorders / history*
  • Netherlands
  • Psychiatry / history*
  • Psychiatry / standards

Substances

  • Chlorpromazine