Stem cell maintenance of the mammary gland: it takes two

Patricia J Keller; Lisa M Arendt; Charlotte Kuperwasser

doi:10.1016/j.stem.2011.11.008

Stem cell maintenance of the mammary gland: it takes two

Cell Stem Cell. 2011 Dec 2;9(6):496-7. doi: 10.1016/j.stem.2011.11.008.

Authors

Patricia J Keller¹, Lisa M Arendt, Charlotte Kuperwasser

Affiliation

¹ Department of Anatomy and Cellular Biology, Sackler School, Tufts University School of Medicine, Boston, MA 02111, USA.

PMID: 22136921
DOI: 10.1016/j.stem.2011.11.008

Abstract

Transplantation assays suggest that multipotent stem cells maintain the two lineages of the mammary gland. Recently in Nature, Van Keymeulen et al. (2011) used lineage tracing to discover unipotent stem cells that maintain the bulk of the mouse mammary gland after birth and during pregnancy.

Publication types

Comment

Grants and funding

R01 HD073035/HD/NICHD NIH HHS/United States