Abstract
In 1977, Carl Woese and George Fox published a brief paper in PNAS that established, for the first time, that the overall phylogenetic structure of the living world is tripartite. We describe the way in which this monumental discovery was made, its context within the historical development of evolutionary thought, and how it has impacted our understanding of the emergence of life and the characterization of the evolutionary process in its most general form.
Publication types
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Historical Article
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Archaea / genetics*
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Bacteria / genetics*
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Biological Evolution*
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Classification / methods
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Eukaryota / genetics*
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History, 20th Century
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Microbiology / history*
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Molecular Biology / history*
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Oligonucleotides / genetics
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Phylogeny*
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RNA, Ribosomal, 16S / genetics
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Sequence Analysis, DNA / methods
Substances
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Oligonucleotides
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RNA, Ribosomal, 16S