Brugada syndrome phenotype cardiac arrest in a young patient unmasked during the acute phase of amiodarone infusion: disclosure and aggravation of Brugada electrocardiographic pattern

Antonio D'Aloia; Enrico Vizzardi; Silvia Bugatti; Gregoriana Zanini; Luca Bontempi; Antonio Curnis

doi:10.1016/j.jelectrocard.2012.02.005

Brugada syndrome phenotype cardiac arrest in a young patient unmasked during the acute phase of amiodarone infusion: disclosure and aggravation of Brugada electrocardiographic pattern

J Electrocardiol. 2012 Jul-Aug;45(4):411-413. doi: 10.1016/j.jelectrocard.2012.02.005. Epub 2012 Mar 16.

Authors

Antonio D'Aloia¹, Enrico Vizzardi², Silvia Bugatti¹, Gregoriana Zanini¹, Luca Bontempi¹, Antonio Curnis¹

Affiliations

¹ Section of Cardiovascular Diseases, Department of Experimental and Applied Medicine, University of Brescia, Brescia, Italy.
² Section of Cardiovascular Diseases, Department of Experimental and Applied Medicine, University of Brescia, Brescia, Italy. Electronic address: enrico.vizzardi@tin.it.

PMID: 22425290
DOI: 10.1016/j.jelectrocard.2012.02.005

Abstract

We report a case of an outpatient cardiac arrest due to ventricular fibrillation and resuscitated with external automated defibrillator shocks in which acute amiodarone infusion unmasked a Brugada phenotype electrocardiographic pattern. Possible interferences by this drug and suitable therapeutic actions are discussed.

Publication types

Case Reports

MeSH terms

Adult
Amiodarone / administration & dosage*
Amiodarone / adverse effects
Anti-Arrhythmia Agents / administration & dosage*
Anti-Arrhythmia Agents / adverse effects
Brugada Syndrome / chemically induced
Brugada Syndrome / diagnosis*
Electrocardiography*
Heart Arrest / drug therapy*
Heart Arrest / physiopathology
Humans
Infusions, Intravenous
Male
Phenotype

Substances

Anti-Arrhythmia Agents
Amiodarone