Single-molecule imaging: a collagenase pauses before embarking on a killing spree

Curr Biol. 2012 Jun 19;22(12):R499-501. doi: 10.1016/j.cub.2012.04.037.

Authors

Gwangrog Lee¹, Taekjip Ha

Affiliation

¹ School of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 500-712, Korea.

PMID: 22720688
DOI: 10.1016/j.cub.2012.04.037

Abstract

Single-molecule tracking provides new insights into how an ATP-independent endo-proteolytic machine digests collagen fibrils during their remodeling.

Copyright © 2012 Elsevier Ltd. All rights reserved.

Publication types

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MeSH terms

Animals
Collagen Type I / metabolism*
Matrix Metalloproteinase 1 / metabolism*
Models, Biological*
Proteolysis*

Substances

Collagen Type I
Matrix Metalloproteinase 1