NHLBI clinical trials workshop: an executive summary

Gang Zheng; Colin O Wu; Song Yang; Myron A Waclawiw; David L DeMets; Nancy L Geller

doi:10.1002/sim.5406

NHLBI clinical trials workshop: an executive summary

Stat Med. 2012 Nov 10;31(25):2938-43. doi: 10.1002/sim.5406. Epub 2012 Jun 26.

Authors

Gang Zheng¹, Colin O Wu, Song Yang, Myron A Waclawiw, David L DeMets, Nancy L Geller

Affiliation

¹ Office of Biostatistics Research, Division of Cardiovascular Sciences, National Heart, Lung and Blood Institute, Bethesda, MD 20892, U.S.A. zhengg@nhlbi.nih.gov

PMID: 22733431
DOI: 10.1002/sim.5406

Abstract

On September 13-14, 2010, the National Heart, Lung and Blood Institute (NHLBI) organized a workshop: 'Clinical Trials: Past, Present and Future'. The workshop covered many areas in clinical trials, including the history of clinical trials at NHLBI, Bayesian clinical trials, surrogate endpoints, reporting clinical trials, handling missing data, flexible designs and adaptive trials, personalized medicine and genomic clinical trials, and comparative effectiveness research. In this report, we summarize the main discussions and conclusions based on the presentations of the invited speakers at the workshop.

Publication types

Historical Article

MeSH terms

Clinical Trials as Topic* / history
Clinical Trials as Topic* / methods
Clinical Trials as Topic* / statistics & numerical data
History, 20th Century
Humans
National Heart, Lung, and Blood Institute (U.S.)*
Randomized Controlled Trials as Topic / trends
Research Personnel / education*
United States