Abstract
A nickel-catalyzed decarbonylative C-H biaryl coupling of azoles and aryl esters is described. The newly developed catalytic system does not require the use of expensive metal catalysts or silver- or copper-based stoichiometric oxidants. We have successfully applied this new C-H arylation reaction to a convergent formal synthesis of muscoride A.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Azoles / chemical synthesis
-
Azoles / chemistry*
-
Catalysis
-
Esters / chemistry
-
Models, Molecular
-
Nickel / chemistry*
-
Oxazoles / chemical synthesis*
-
Oxazoles / chemistry
-
Pyrrolidines / chemical synthesis*
-
Pyrrolidines / chemistry
Substances
-
Azoles
-
Esters
-
Oxazoles
-
Pyrrolidines
-
muscoride A
-
Nickel