A novel G1 checkpoint mediated by the p57 CDK inhibitor and p38 SAPK promotes cell survival upon stress

Cell Cycle. 2012 Sep 15;11(18):3339-40. doi: 10.4161/cc.21840. Epub 2012 Aug 23.

Abstract

Comment on: Joaquin M, et al. EMBO J 2012; 31:2952-64.

Publication types

  • Editorial

MeSH terms

  • Animals
  • Cell Survival
  • Cyclin-Dependent Kinase Inhibitor p57 / metabolism*
  • Enzyme Activation
  • G1 Phase Cell Cycle Checkpoints*
  • Humans
  • Models, Biological
  • Osmotic Pressure
  • Phosphorylation
  • Stress, Physiological*
  • p38 Mitogen-Activated Protein Kinases / metabolism*

Substances

  • Cyclin-Dependent Kinase Inhibitor p57
  • p38 Mitogen-Activated Protein Kinases