Proximal hamstring injuries can be disabling, and several traditional conservative treatments, including physiotherapy and nonsteroidal anti-inflammatory drugs, have been inconsistent. Corticosteroid injections have demonstrated success but can adversely affect local tissues. Platelet-rich plasma (PRP) has emerged as a safe, effective treatment for several orthopedic pathologies. The authors propose a PRP injection at the muscle origin as a novel treatment for proximal hamstring injuries. A retrospective review yielded 15 patients with 17 proximal hamstring injuries. Twelve injuries failed traditional conservative treatment and were ultimately treated with a PRP injection at the hamstrings muscle origin. Five patients were treated with traditional conservative treatment alone. Analysis included pre- and posttreatment visual analog scale scores, Nirschl Phase Rating Scale scores, and return to sport. No significant difference existed between the groups' pretreatment visual analog scale scores (P=.28) and Nirschl Phase Rating Scale scores (P=.15) and their posttreatment visual analog scale scores (P=.38) and Nirschl Phase Rating Scale scores (P=.22). The PRP group demonstrated a reduction in visual analog scale scores (P<.01) and Nirschl Phase Rating Scale scores (P<.01), but the traditional conservative treatment group did not demonstrate the same reduction (P=.06 and .06, respectively). All athletes returned to their desired activity level with no major complications.
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