Infiltrating lobular breast cancer: truly a separate entity! Consequences for radiation therapy

Philip M P Poortmans; Marc Bollet; Erik Van Limbergen

doi:10.1016/j.radonc.2012.12.010

Infiltrating lobular breast cancer: truly a separate entity! Consequences for radiation therapy

Radiother Oncol. 2013 Jan;106(1):1-4. doi: 10.1016/j.radonc.2012.12.010. Epub 2013 Jan 22.

Authors

Philip M P Poortmans¹, Marc Bollet, Erik Van Limbergen

Affiliation

¹ Department of Radiation Oncology, Institute Verbeeten, Tilburg, The Netherlands. Poortmans.ph@bvi.nl

PMID: 23351846
DOI: 10.1016/j.radonc.2012.12.010

Abstract

Infiltrating lobular cancer is known for its diffuse growth pattern and difficult radiological visualization. Based on this review, infiltrating lobular cancer patients do not have a higher local recurrence risk after breast conserving therapy. Lobular histology should also be considered as a separate prognostic factor in favour of referral for radiotherapy after mastectomy.

MeSH terms

Breast Neoplasms / radiotherapy*
Carcinoma, Lobular / radiotherapy*
Female
Humans
Mastectomy
Mastectomy, Segmental