Gold biomineralization by a metallophore from a gold-associated microbe

Nat Chem Biol. 2013 Apr;9(4):241-3. doi: 10.1038/nchembio.1179. Epub 2013 Feb 3.

Abstract

Microorganisms produce and secrete secondary metabolites to assist in their survival. We report that the gold resident bacterium Delftia acidovorans produces a secondary metabolite that protects from soluble gold through the generation of solid gold forms. This finding is the first demonstration that a secreted metabolite can protect against toxic gold and cause gold biomineralization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Coordination Complexes / chemistry
  • Coordination Complexes / metabolism*
  • Cupriavidus / genetics
  • Cupriavidus / metabolism
  • Delftia acidovorans / genetics
  • Delftia acidovorans / metabolism*
  • Gold / metabolism*
  • Magnetic Resonance Spectroscopy
  • Metal Nanoparticles / chemistry*
  • Peptides / genetics
  • Peptides / metabolism*
  • Solubility

Substances

  • Bacterial Proteins
  • Coordination Complexes
  • Peptides
  • Gold

Associated data

  • PubChem-Substance/160657715
  • PubChem-Substance/160657716