[Hyponatremic encephalopathy with non-cardiogenic pulmonary edema. Development following marathon run]

Med Klin Intensivmed Notfmed. 2013 Apr;108(3):234-7. doi: 10.1007/s00063-012-0198-7. Epub 2012 Dec 21.
[Article in German]

Abstract

This article presents the case of a 52-year-old woman who developed exercise-associated hyponatremia (EAH) complicated by non-cardiogenic pulmonary edema after a marathon run. The condition of EAH is a potentially life-threatening complication of endurance exercise. The main cause seems to be inadequate intake of free water during or following exercise with enduring antidiuresis due to nonosmotic stimulation of ADH secretion. Known risk factors are female gender, slow running pace and lack of weight loss. Emergency therapy is fluid restriction and bolus infusion of 3% NaCl solution to rapidly reduce brain edema.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Brain Diseases, Metabolic / diagnosis
  • Brain Diseases, Metabolic / etiology*
  • Brain Diseases, Metabolic / therapy*
  • Brain Edema / diagnosis
  • Brain Edema / etiology*
  • Brain Edema / therapy*
  • Critical Care / methods*
  • Diagnosis, Differential
  • Female
  • Germany
  • Humans
  • Hyponatremia / diagnosis
  • Hyponatremia / etiology*
  • Hyponatremia / therapy*
  • Middle Aged
  • Physical Endurance*
  • Pulmonary Edema / diagnosis
  • Pulmonary Edema / etiology*
  • Pulmonary Edema / therapy*
  • Rhabdomyolysis / diagnosis
  • Rhabdomyolysis / etiology
  • Rhabdomyolysis / therapy
  • Risk Factors
  • Running*
  • Sodium Chloride / administration & dosage
  • Tomography, X-Ray Computed

Substances

  • Sodium Chloride