NPMc+ and FLT3_ITD mutations cooperate in inducing acute leukaemia in a novel mouse model

Leukemia. 2013 Nov;27(11):2248-51. doi: 10.1038/leu.2013.114. Epub 2013 Apr 15.

Authors

M Mallardo¹, A Caronno, G Pruneri, P R Raviele, A Viale, P G Pelicci, E Colombo

Affiliation

¹ Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.

PMID: 23584564
DOI: 10.1038/leu.2013.114

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Acute Disease
Animals
Disease Models, Animal*
Female
Humans
Leukemia / genetics
Leukemia / metabolism
Leukemia / pathology*
Male
Mice
Mice, Inbred C57BL
Mutation / genetics*
Nuclear Proteins / physiology*
Nucleophosmin
Survival Rate
Tandem Repeat Sequences / genetics*
fms-Like Tyrosine Kinase 3 / genetics*

Substances

Nuclear Proteins
Nucleophosmin
FLT3 protein, human
fms-Like Tyrosine Kinase 3