Genotype 4 hepatitis e virus in france: an autochthonous infection with a more severe presentation

Clin Infect Dis. 2013 Aug;57(4):e122-6. doi: 10.1093/cid/cit291. Epub 2013 May 10.

Abstract

Among hepatitis E virus (HEV) infections diagnosed in 2011 by the French Reference Centre for HEV, 9 were due to genotype 4, which until recently was limited to Asia. Sequences from autochthonous cases formed a single cluster very similar to Belgian swine sequences. Clinical presentation differed from genotype 3 infections.

Keywords: HEV; HEV genotype 4; epidemiology; virulence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cluster Analysis
  • Female
  • France / epidemiology
  • Genotype
  • Hepatitis E / epidemiology*
  • Hepatitis E / pathology*
  • Hepatitis E / virology
  • Hepatitis E virus / classification*
  • Hepatitis E virus / genetics*
  • Hepatitis E virus / isolation & purification
  • Humans
  • Male
  • Middle Aged
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics
  • Sequence Analysis, DNA

Substances

  • RNA, Viral

Associated data

  • GENBANK/KC437301
  • GENBANK/KC437302
  • GENBANK/KC437303
  • GENBANK/KC437304
  • GENBANK/KC437305
  • GENBANK/KC437306
  • GENBANK/KC437307
  • GENBANK/KC437308
  • GENBANK/KC437309
  • GENBANK/KC437310
  • GENBANK/KC437311
  • GENBANK/KC437312
  • GENBANK/KC437313
  • GENBANK/KC437314
  • GENBANK/KC437315
  • GENBANK/KC437316
  • GENBANK/KC437317