Breast osteosarcoma 29 years after radiation therapy for epithelial breast cancer

Case Rep Oncol. 2013 Jul 11;6(2):367-72. doi: 10.1159/000353888. Print 2013 May.

Abstract

Radiation therapy has a solid role in the management of breast adenocarcinoma. It significantly reduces the rates of disease recurrence. Nevertheless, radiation therapy is not without side effects and patients who have undergone breast irradiation are at increased risk for lung disease, sarcomas, acute leukemia and esophageal cancer. We present a case of radiation-induced breast osteosarcoma 29 years after radiation therapy and lumpectomy for breast adenocarcinoma. The patient had several disease recurrences after surgical resection and was found to have pulmonary metastases.

Keywords: Breast osteosarcoma; Epithelial breast cancer; Radiation therapy.

Publication types

  • Case Reports