Effects of vibration therapy on hormone response and stress in severely disabled patients: a double-blind randomized placebo-controlled clinical trial

Rehabil Nurs. 2015 May-Jun;40(3):166-78. doi: 10.1002/rnj.116. Epub 2013 Aug 6.

Abstract

Purpose: To assess the effects of vibration therapy (VT) on quality of life and hormone response in severely disabled patients compared with placebo.

Design: A longitudinal prospective, double-blind, randomized placebo-controlled trial, with pre and postintervention assessments.

Methods: A total of 20 severely disabled individuals were recruited from a National Reference Centre in Spain: 13 (65%) men and 7 (35%) women, 45.5 ± 9.32 years of age (range 41: 22-63). We evaluated their physical stress and state anxiety.

Results: No statistically significant changes were found in the socio-psychological variables studied, while in the experimental group state anxiety decreased significantly with p < 0.01 (Z = 2.38; one-tailed p = .009) and, among the biological variables, the level of cortisol fell (p = 0.03).

Conclusion: Short periods of exposure to low-frequency and low-amplitude local vibration are a safe and effective mechanical stimulus that can have a positive effect in terms of hormone response.

Clinical relevance: VT can be considered to have an anti-stress effect.

Keywords: Vibration therapy; anxiety state; cortisol; hormone response; severe disability; stress; testosterone.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Disabled Persons / rehabilitation*
  • Double-Blind Method
  • Female
  • Hormones / metabolism*
  • Humans
  • Male
  • Middle Aged
  • Nervous System Diseases / metabolism*
  • Nervous System Diseases / nursing
  • Nervous System Diseases / therapy*
  • Prospective Studies
  • Quality of Life
  • Rehabilitation Nursing / methods*
  • Spain
  • Vibration / therapeutic use*
  • Young Adult

Substances

  • Hormones