Abstract
We compared antibodies against human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) in children. The antibody nadirs for both viruses were at 3 to 5 months, and the majority of children were seropositive for both by 2 years. There was no significant difference in the kinetics of maternal antibody decline or seroconversion relative to the two viruses.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Age Factors
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Antibodies, Viral / blood*
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Antigens, Viral* / genetics
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Child
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Child, Preschool
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Enzyme-Linked Immunosorbent Assay / methods
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Female
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Humans
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Infant
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Infant, Newborn
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Male
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Metapneumovirus / immunology*
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Paramyxoviridae Infections / epidemiology*
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Paramyxoviridae Infections / immunology
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Recombinant Fusion Proteins / genetics
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Respiratory Syncytial Virus Infections / epidemiology*
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Respiratory Syncytial Virus Infections / immunology
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Respiratory Syncytial Virus, Human / immunology*
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Seroepidemiologic Studies
Substances
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Antibodies, Viral
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Antigens, Viral
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Recombinant Fusion Proteins