Pseudokiller, qu'est-ce que c'est?

Immunity. 2013 Sep 19;39(3):421-2. doi: 10.1016/j.immuni.2013.08.020.

Abstract

Necroptosis is mediated by engagement of RIP kinases and a downstream pseudokinase, MLKL. In this issue of Immunity, Murphy et al. (2013) show that it operates at or close to the final execution mechanism of the death process.

Publication types

  • Comment

MeSH terms

  • Animals
  • Apoptosis*
  • Protein Kinases / metabolism*
  • Receptor-Interacting Protein Serine-Threonine Kinases / metabolism*
  • Tumor Necrosis Factors / metabolism*

Substances

  • Tumor Necrosis Factors
  • MLKL protein, mouse
  • Protein Kinases
  • Receptor-Interacting Protein Serine-Threonine Kinases
  • Ripk3 protein, mouse