Abstract
Clinical question:
Do statins reduce rates of cardiovascular events when used for primary prevention?
Bottom line:
When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
MeSH terms
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Cardiovascular Diseases / mortality
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Cardiovascular Diseases / prevention & control*
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Evidence-Based Medicine
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Humans
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects
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Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use*
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Neoplasms / epidemiology
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Primary Prevention*
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Randomized Controlled Trials as Topic
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Risk
Substances
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Hydroxymethylglutaryl-CoA Reductase Inhibitors