[Current results with surgery and adjuvant chemotherapy in malignant melanoma]

Arch Geschwulstforsch. 1986;56(5):367-71.
[Article in German]

Abstract

The paper presents the results of three randomized trials for adjuvant chemo- and immunotherapy in malignant melanoma clinical stage II: 770 patients were treated by surgery, surgery + DTIC, surgery + BCG or surgery + DTIC + BCG, 248 patients were treated by surgery or surgery + poly-U-A; 40 patients were treated by surgery or surgery + vinblastine/bleomycine/cisplatinum. Neither the recidive free interval nor the survival could be enhanced by surgically adjuvant chemo- and immunotherapy in this group of patients.

Publication types

  • Clinical Trial
  • English Abstract
  • Randomized Controlled Trial

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • BCG Vaccine / therapeutic use
  • Bleomycin / administration & dosage
  • Cisplatin / administration & dosage
  • Clinical Trials as Topic
  • Dacarbazine / therapeutic use
  • Humans
  • Melanoma / drug therapy
  • Melanoma / surgery
  • Melanoma / therapy*
  • Random Allocation
  • Vinblastine / administration & dosage

Substances

  • BCG Vaccine
  • Bleomycin
  • Vinblastine
  • Dacarbazine
  • Cisplatin

Supplementary concepts

  • PVB protocol