A review on anti-inflammatory activity of phenylpropanoids found in essential oils

Molecules. 2014 Jan 27;19(2):1459-80. doi: 10.3390/molecules19021459.

Abstract

The search for alternative drugs capable of disrupting the inflammatory process has become an important issue in scientific research, especially with reference to the use of natural substances and the reduction of undesirable side effects. Essential oils represent an important source of such substances, since their active constituents often exhibit an array of pharmacological properties, including anti-inflammatory activity. This review presents an overview of the anti-inflammatory action exerted by phenylpropanoids from essential oils and discusses possible mechanisms of action involved in the anti-inflammatory response, assessed through specific experimental models.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / pharmacology
  • Asthma / drug therapy
  • Asthma / pathology
  • Biological Products / administration & dosage
  • Biological Products / chemistry*
  • Cinnamates / chemistry
  • Cytokines / immunology
  • Cytokines / metabolism
  • Humans
  • Hypersensitivity / drug therapy
  • Hypersensitivity / pathology
  • Immunomodulation / drug effects
  • Inflammation / drug therapy*
  • Inflammation / immunology
  • Oils, Volatile / administration & dosage
  • Oils, Volatile / chemistry*
  • Phenylalanine / chemistry
  • Plants, Medicinal / chemistry*

Substances

  • Anti-Inflammatory Agents
  • Biological Products
  • Cinnamates
  • Cytokines
  • Oils, Volatile
  • cinnamic acid
  • Phenylalanine