Chancroid, lymphogranuloma venereum, granuloma inguinale, genital herpes simplex infection, and molluscum contagiosum

Clin Dermatol. 2014 Mar-Apr;32(2):290-8. doi: 10.1016/j.clindermatol.2013.08.013.

Abstract

Chancroid, lymphogranuloma venereum, and granuloma inguinale may be considered as tropical venereal diseases. These diseases were a major diagnostic and therapeutic challenge in past centuries. Currently, patients with these bacterial infections that are endemic to the tropics occasionally consult with dermatologists in temperate climates. Due to the increasing frequency of travel to the tropics for tourism and work, as well as the increasing number of immigrants from these areas, it is important for dermatologists practicing in temperate climates to be familiar with the dermatologic manifestations of such infections, to be prepared to diagnose these diseases, and to treat these patients. All three "tropical" infections respond well to prompt and appropriate antimicrobial treatment, although herpes progenitalis still cannot be cured, and the number of people infected keeps growing; moreover, genital herpes can be transmitted by viral shedding before and after the visual signs or symptoms. Acyclovir, valacyclovir, and famciclovir can shorten outbreaks and make them less severe or even stop them from happening. There is currently no etiologic treatment for molluscum contagiosum, and the majority of treatment options are mechanical, causing a certain degree of discomfort. The molluscum contagiosum virus, unlike the other infectious agents mentioned, does not invade the skin.

Publication types

  • Review

MeSH terms

  • Chancroid / diagnosis
  • Chancroid / drug therapy*
  • Chancroid / epidemiology*
  • Chancroid / microbiology
  • Granuloma Inguinale / diagnosis*
  • Granuloma Inguinale / drug therapy
  • Granuloma Inguinale / microbiology
  • Granuloma Inguinale / transmission
  • Herpes Genitalis / diagnosis*
  • Herpes Genitalis / drug therapy*
  • Herpes Genitalis / virology
  • Humans
  • Lymphogranuloma Venereum / complications*
  • Lymphogranuloma Venereum / diagnosis
  • Lymphogranuloma Venereum / drug therapy
  • Lymphogranuloma Venereum / epidemiology
  • Molluscum Contagiosum / diagnosis
  • Molluscum Contagiosum / therapy*
  • Molluscum Contagiosum / virology