Tuberculosis exposure, infection and disease among children with medical comorbidities

Pediatr Infect Dis J. 2014 Aug;33(8):885-8. doi: 10.1097/INF.0000000000000343.

Abstract

Sixty-nine children with medical comorbidities were treated for tuberculosis (TB) exposure (7), infection (40) or disease (22). The most common comorbidities in children with TB disease were malignancy (23%), cyanotic heart disease (18%), hemoglobinopathies (18%) and autoimmune disease (14%). Ninety-six percent who received TB medications had no adverse events and 98% completed therapy. Two (9%) died of TB.

MeSH terms

  • Adolescent
  • Anemia, Sickle Cell / epidemiology
  • Child
  • Child, Preschool
  • Comorbidity
  • Female
  • Heart Diseases / epidemiology
  • Humans
  • Infant
  • Inflammatory Bowel Diseases / epidemiology
  • Male
  • Neoplasms / epidemiology
  • Retrospective Studies
  • Texas / epidemiology
  • Tuberculosis / epidemiology*