Abstract
The neuropeptide substance P modulates the activities of a number of different leukocytes that characterize both acute and delayed inflammatory responses. Substance P may play a role in the pathogenesis of such diverse diseases as arthritis, asthma, and inflammatory bowel disease.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Humans
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Hypersensitivity, Delayed / physiopathology
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Hypersensitivity, Immediate / physiopathology
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Inflammation / physiopathology*
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Mononuclear Phagocyte System / drug effects
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Muscle, Smooth / drug effects
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Receptors, Neurokinin-1
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Receptors, Neurotransmitter / drug effects
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Substance P / physiology*
Substances
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Receptors, Neurokinin-1
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Receptors, Neurotransmitter
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Substance P