Various forms of perimetry are used to confirm Chloroquine retinopathy diagnosed by Amsler grid testing. Little is known about the value of using a red target generated statically. The purpose of this study was to determine the sensitivity and specificity of both red and white perimetry using program 10-2 on the Humphrey automated perimeter. Sixty-nine eyes were tested in total. Fifty eyes were from patients with known early Chloroquine retinopathy with abnormal Amslers. Red perimetry was 91.3% sensitive and 57.8% specific for Chloroquine retinopathy. White perimetry was 78% sensitive and 84% specific for this condition. In conclusion, red Humphrey perimetry was highly sensitive but not highly specific for Chloroquine retinopathy.