Additive effect of combined spironolactone and phenobarbital treatment on hepatic bilirubin UDP-glucuronyltransferase

Biochem Pharmacol. 1989 Mar 1;38(5):851-3. doi: 10.1016/0006-2952(89)90240-2.

Authors

A D Mottino¹, E E Guibert, E A Rodríguez Garay

Affiliation

¹ Instituto de Fisiología Experimental, Facultad de Ciencias, Bioquímicas y Farmacéuticas-U.N.R., Rosario, Argentina.

PMID: 2495006
DOI: 10.1016/0006-2952(89)90240-2

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Body Weight / drug effects
Drug Synergism
Enzyme Induction / drug effects
Glucuronosyltransferase / biosynthesis*
Male
Microsomes, Liver / drug effects
Microsomes, Liver / enzymology*
Organ Size / drug effects
Phenobarbital / pharmacology*
Rats
Rats, Inbred Strains
Spironolactone / pharmacology*

Substances

Spironolactone
Glucuronosyltransferase
Phenobarbital