Abstract
Topical agents that do not produce irritant reaction elsewhere on the skin readily produce irritant dermatitis and even ulceration when applied to scrotal skin. As Shelley and Shelley state: "The scrotum must be recognized as a skin area with remarkable permeability. It provides a unique percutaneous doorway for the entrance of drugs into the circulation and is thus uniquely susceptible to toxic and irritant agents."
MeSH terms
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Administration, Cutaneous
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Adult
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Aluminum Hydroxide / adverse effects
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Astringents / adverse effects
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Drug Eruptions / etiology*
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Hair Removal / adverse effects
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Humans
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Irritants / adverse effects*
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Male
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Podophyllin / adverse effects
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Scrotum / drug effects*
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Thioglycolates / adverse effects
Substances
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Astringents
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Irritants
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Thioglycolates
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aluminum oxychloride
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Aluminum Hydroxide
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2-mercaptoacetate
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Podophyllin