Recombinant tissue plasminogen activators (rtPA): a review

Clin Pharmacol Ther. 2015 Mar;97(3):274-85. doi: 10.1002/cpt.33. Epub 2015 Jan 31.

Authors

P Gurman¹, O R Miranda, A Nathan, C Washington, Y Rosen, N M Elman

Affiliation

¹ Institute for Soldier Nanotechnologies, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA; Department of Materials Science and Bioengineering, University of Texas at Dallas, Richardson, Texas, USA.

PMID: 25670034
DOI: 10.1002/cpt.33

No abstract available

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Drug Delivery Systems / methods
Drug Monitoring / methods
Humans
Myocardial Infarction / drug therapy*
Plasminogen / drug effects*
Plasminogen / metabolism
Pulmonary Embolism / drug therapy*
Recombinant Proteins / administration & dosage
Recombinant Proteins / pharmacology
Recombinant Proteins / therapeutic use*
Stroke / drug therapy*
Thrombolytic Therapy / methods*
Tissue Plasminogen Activator / administration & dosage
Tissue Plasminogen Activator / pharmacology
Tissue Plasminogen Activator / therapeutic use*

Substances

Recombinant Proteins
Plasminogen
Tissue Plasminogen Activator