Treatment of Ebola virus infection with antibodies from reconvalescent donors

Emerg Infect Dis. 2015 Mar;21(3):521-3. doi: 10.3201/eid2103.141838.

Abstract

Clinical evidence suggests that antibodies from reconvalescent donors (persons who have recovered from infection) may be effective in the treatment of Ebola virus infection. Administration of this treatment to Ebola virus-infected patients while preventing the transmission of other pathogenic viruses may be best accomplished by use of virus-inactivated reconvalescent plasma.

MeSH terms

  • Antibodies, Viral / therapeutic use*
  • Blood Donors
  • Ebolavirus / immunology*
  • Hemorrhagic Fever, Ebola / immunology*
  • Hemorrhagic Fever, Ebola / therapy*
  • Humans
  • Immune Sera
  • Plasma / immunology*

Substances

  • Antibodies, Viral
  • Immune Sera