CADASIL presenting as schizophreniform organic psychosis

Abstract

Objective: To describe an Asian patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) presenting with schizophreniform organic psychosis.

Methods: Case report.

Results: We report a case of CADASIL in an Asian female presenting with frank psychotic symptoms. After resolution of her psychosis, she showed persistent distractibility, which indicated signs of cognitive impairment.

Conclusion: Although neuropsychiatric symptoms are commonly present in this disorder, psychotic symptoms are rare and should be recognized. There is a need for timely diagnosis and management of this disorder.

Keywords: Asian; CADASIL; Neuropsychiatric symptoms; Schizophreniform organic psychosis.