Rhabdomyolysis: pathogenesis, diagnosis, and treatment

Patrick A Torres; John A Helmstetter; Adam M Kaye; Alan David Kaye

Rhabdomyolysis: pathogenesis, diagnosis, and treatment

Ochsner J. 2015 Spring;15(1):58-69.

Authors

Patrick A Torres¹, John A Helmstetter¹, Adam M Kaye², Alan David Kaye³

Affiliations

¹ Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA.
² Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA.
³ Department of Anesthesiology, Louisiana State University Health Sciences Center, New Orleans, LA ; Department of Pharmacology, Louisiana State University Health Sciences Center, New Orleans, LA.

PMID: 25829882
PMCID: PMC4365849

Abstract

Background: Rhabdomyolysis is a complex medical condition involving the rapid dissolution of damaged or injured skeletal muscle.

Methods: This review focuses on the epidemiology, pathophysiology, causes, presentation, diagnosis, complications, management, and anesthetic considerations related to rhabdomyolysis.

Results: Any form of muscle damage--and by extension any entity that causes muscle damage--can initiate rhabdomyolysis. One of the most important treatment goals when rhabdomyolysis is suspected is avoiding acute kidney injury.

Conclusion: All clinicians should be aware of common causes, diagnosis, and treatment options.

Keywords: Rhabdomyolysis.

Publication types

Review