Examine association between socio-demographic characteristics and breastfeeding knowledge, self-efficacy and breastfeeding attrition prediction among rural Hispanic women. 46 rural Hispanic women, aged 18-38 years were enrolled from Regional West Medical Center, Scottsbluff, Nebraska. Intervention (n = 23) and attention control groups (n = 23) received bi-lingual breastfeeding education using touch screen computer and printed educational material. Participants were enrolled during last 6 weeks of pregnancy. Follow up assessments were at days 3 and 7, weeks 2 and 6, and months 3 and 6 postpartum. More than half of participants were single and had 10-12 years of education. Less than half of them had ever breastfed their children. No differences in knowledge, self-efficacy and intent to breastfeed scores were seen between two groups. Significant positive association was seen between self-efficacy and intent to breastfeed. Self-efficacy is an important predictor of intent to breastfeed among rural Hispanic women.