Predictors of Outcome of Convulsive Status Epilepticus Among an Egyptian Pediatric Tertiary Hospital

J Child Neurol. 2015 Nov;30(13):1736-42. doi: 10.1177/0883073815579706. Epub 2015 Apr 20.

Abstract

Convulsive status epilepticus is a common neurologic emergency in pediatrics. We aimed to study the etiology, clinical features, and prognostic factors among pediatric patients with convulsive status epilepticus. Seventy patients were included in this cohort study from pediatric emergency department of the specialized Children Hospital of Cairo University. The outcome was evaluated using the Glasgow Outcome Score. Acute symptomatic etiology was the most common cause of convulsive status epilepticus. Refractory convulsive status epilepticus was observed more significantly in cases caused by acute symptomatic etiologies. The outcome was mortality in 26 (37.1%) patients, severe disability in 15 (21.4%), moderate disability in 17 (24.3%), and good recovery in 12 (17.1%) patients. The significant predictor of mortality was lower modified Glasgow Coma Scale score on admission, whereas lower modified Glasgow Coma Scale score on admission and refractory convulsive status epilepticus were the significant predictors for disability and mortality.

Keywords: convulsive status epilepticus; outcome; predictors.

MeSH terms

  • Child
  • Child, Preschool
  • Cohort Studies
  • Disability Evaluation
  • Egypt
  • Female
  • Glasgow Coma Scale
  • Glasgow Outcome Scale
  • Hospitals, University
  • Humans
  • Infant
  • Male
  • Prognosis
  • Status Epilepticus / diagnosis*
  • Status Epilepticus / etiology
  • Status Epilepticus / mortality
  • Status Epilepticus / therapy*
  • Tertiary Care Centers
  • Treatment Outcome