[Isolation of pomolic acid from Chamaenerion angustifolium and evaluation of its genotoxicity by microbiological tests]

T S Frolova; O I Salnikova; T A Dudareva; T P Kukina; O I Synitsyna

doi:10.1134/s1068162013060046

[Isolation of pomolic acid from Chamaenerion angustifolium and evaluation of its genotoxicity by microbiological tests]

Bioorg Khim. 2014 Jan-Feb;40(1):92-8. doi: 10.1134/s1068162013060046.

[Article in Russian]

Authors

T S Frolova, O I Salnikova, T A Dudareva, T P Kukina, O I Synitsyna

PMID: 25898727
DOI: 10.1134/s1068162013060046

Abstract

Fireweed (Chamaenerion angustifolium) lipophilic constituents were investigated by GC-MS analysis. 28 aliphatic and 6 triterpenic acids were found out at first time. Pomolic acid genotoxicity and mutagenicity were analyzed by Ames test and SOS chromotest. Genotoxic and mutagenic properties of pomolic acid were not detected.

MeSH terms

Escherichia coli / drug effects
Escherichia coli / genetics
Gas Chromatography-Mass Spectrometry
Mutagenicity Tests / methods*
Mutagens / toxicity
Oleanolic Acid / analogs & derivatives*
Oleanolic Acid / isolation & purification
Oleanolic Acid / toxicity
Onagraceae / chemistry*
SOS Response, Genetics / drug effects
Salmonella typhimurium / drug effects
Salmonella typhimurium / genetics

Substances

Mutagens
pomolic acid
Oleanolic Acid