Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms

Matthew C Good

doi:10.1016/j.devcel.2015.05.015

Turn Up the Volume: Uncovering Nucleus Size Control Mechanisms

Dev Cell. 2015 Jun 8;33(5):496-7. doi: 10.1016/j.devcel.2015.05.015.

Author

Matthew C Good¹

Affiliation

¹ Department of Cell and Developmental Biology and Department of Bioengineering, University of Pennsylvania, 421 Curie Blvd, Philadelphia, PA 19104, USA. Electronic address: mattgood@mail.med.upenn.edu.

PMID: 26058052
DOI: 10.1016/j.devcel.2015.05.015

Abstract

Reporting in Developmental Cell, Hara and Merten (2015) apply the use of microfabrication and in vitro analysis in cell-free extracts to the old problem of nuclear size control. The authors make insights into the regulation of nuclear growth that potentially explain the widely reported correlation between nucleus size and cell size.

Publication types

Comment

MeSH terms

Animals
Cell Nucleus / physiology*
Dyneins / metabolism*
Female
Microtubules / metabolism*
Nuclear Envelope / physiology*
Oocytes / cytology*
Oocytes / metabolism*
Xenopus laevis / metabolism*

Substances

Dyneins