Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I

Klaus Engelke; Thomas Lang; Sundeep Khosla; Ling Qin; Philippe Zysset; William D Leslie; John A Shepherd; John T Schousboe

doi:10.1016/j.jocd.2015.06.012

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I

J Clin Densitom. 2015 Jul-Sep;18(3):338-58. doi: 10.1016/j.jocd.2015.06.012.

Authors

Klaus Engelke¹, Thomas Lang², Sundeep Khosla³, Ling Qin⁴, Philippe Zysset⁵, William D Leslie⁶, John A Shepherd², John T Schousboe⁷

Affiliations

¹ Institute of Medical Physics, University of Erlangen, Germany; Bioclinica, Hamburg, Germany. Electronic address: klaus.engelke@imp.uni-erlangen.de.
² Department of Radiology and Biomedical Imaging, UCSF School of Medicine, San Francisco, CA, USA.
³ Center for Clinical and Translational Science, Mayo Clinic College of Medicine, Rochester, MN, USA.
⁴ Bone Quality and Health Center, Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, China.
⁵ Institute for Surgical Technology & Biomechanics, University of Bern, Switzerland.
⁶ Department of Medicine, University of Manitoba, Winnipeg, Canada; Department of Radiology, University of Manitoba, Winnipeg, Canada.
⁷ Park Nicollet Clinic/HealthPartners, Minneapolis, MN, USA; Division of Health Policy and Management, University of Minnesota, Minneapolis, MN, USA.

PMID: 26277851
DOI: 10.1016/j.jocd.2015.06.012

Abstract

The International Society for Clinical Densitometry (ISCD) has developed new official positions for the clinical use of quantitative computed tomography of the hip. The ISCD task force for quantitative computed tomography reviewed the evidence for clinical applications and presented a report with recommendations at the 2015 ISCD Position Development Conference. Here, we discuss the agreed on ISCD official positions with supporting medical evidence, rationale, controversy, and suggestions for further study. Parts II and III address the advanced techniques of finite element analysis applied to computed tomography scans and the clinical feasibility of existing techniques for opportunistic screening of osteoporosis using computed tomography scans obtained for other diagnosis such as colonography was addressed.

Keywords: Bone mineral density (BMD); Osteoporosis; Position; Proximal femur; Quantitative computed tomography (QCT).

MeSH terms

Absorptiometry, Photon
Acetabulum / diagnostic imaging*
Adult
Bone Density
Consensus
Femur / diagnostic imaging*
Fractures, Bone / etiology*
Humans
Osteoporosis / complications
Osteoporosis / diagnosis*
Practice Guidelines as Topic
Risk Assessment
Societies, Medical
Tomography, X-Ray Computed*