Failure to Validate a Multivariable Clinical Prediction Model to Identify Pediatric Intensive Care Unit Patients at High Risk for Candidemia

J Pediatric Infect Dis Soc. 2016 Dec;5(4):458-461. doi: 10.1093/jpids/piv024. Epub 2015 Apr 29.

Abstract

We attempted to validate a previously derived clinical prediction rule for candidemia in the pediatric intensive care unit. This multicenter case control study did not identify significant association of candidemia with most of the previously identified predictors. Additional study in larger cohorts with other predictor variables is needed.

Keywords: ICU; candidemia; pediatric; prediction; validation.

Publication types

  • Multicenter Study
  • Validation Study

MeSH terms

  • Adolescent
  • Candidemia / diagnosis*
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Decision Support Techniques*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Intensive Care Units, Pediatric*
  • Male