Omeprazole inhibits melanin biosynthesis in melan-a cells and zebrafish

Exp Dermatol. 2016 Mar;25(3):239-41. doi: 10.1111/exd.12915. Epub 2016 Feb 10.

Authors

Seung-hwa Baek¹, Sang-Han Lee^{1

2

3}

Affiliations

¹ Department of Food Science & Biotechnology, Kyungpook National University, Daegu, Korea.
² Department of Nano-Science & Technology, Kyungpook National University, Daegu, Korea.
³ Department of Food & Bio-industry Research Institute, Kyungpook National University, Daegu, Korea.

PMID: 26660505
DOI: 10.1111/exd.12915

No abstract available

Keywords: antimelanogenic effects; melanogenesis-related proteins; microphthalmia-associated transcription factor; omeprazole; zebrafish.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Arbutin / chemistry
Cell Line
Copper / chemistry
Dose-Response Relationship, Drug
Gene Expression Regulation, Developmental / drug effects
Melanins / biosynthesis*
Melanocytes / drug effects*
Mice
Microphthalmia-Associated Transcription Factor / metabolism
Omeprazole / chemistry*
Pigmentation / drug effects
Proton Pump Inhibitors / chemistry
Skin / drug effects*
Tyrosine / chemistry
Zebrafish

Substances

Melanins
Microphthalmia-Associated Transcription Factor
Proton Pump Inhibitors
Tyrosine
Copper
Arbutin
Omeprazole