Severe Coagulopathy after Ingestion of "Snake Wine"

J Emerg Med. 2016 Jun;50(6):848-51. doi: 10.1016/j.jemermed.2015.11.037. Epub 2016 Jan 25.

Abstract

Background: This report describes a patient who developed coagulopathy after ingesting snake wine, which is an alcoholic libation containing an entire venomous snake.

Case report: A 68-year-old man was admitted to the hospital 19 h after ingesting snake wine. The laboratory features upon admission included unmeasurable activated partial thromboplastin (aPTT) values, prolonged prothrombin time (PT) values, increased fibrinogen levels, modestly elevated fibrin degradation product and D-dimer values, uncorrected aPTT and PT values after a mixing test, and normal levels of aspartate transaminase and alanine transaminase. No pesticides, warfarin, or superwarfarin in the patient's blood or urine were detected. His coagulation profile normalized on the 6(th) day after admission after antivenom treatment. He was discharged 10 days later without sequelae. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: The physician should be aware that ingesting snake wine may lead to systemic envenomation. As for coagulopathy, which may develop by ingesting snake venom, related laboratory findings may differ from the features observed after direct envenomation by snakebite.

Keywords: blood coagulation test; serum sickness; snake venoms.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Antivenins / pharmacology
  • Antivenins / therapeutic use
  • Blood Coagulation Disorders / blood
  • Blood Coagulation Disorders / physiopathology*
  • Blood Coagulation Tests
  • Humans
  • Male
  • Serum Sickness / physiopathology*
  • Serum Sickness / therapy
  • Snake Venoms / adverse effects
  • Snakes*
  • Wine / adverse effects*

Substances

  • Antivenins
  • Snake Venoms