Human spinal autografts of olfactory epithelial stem cells recapitulate donor site histology, maintaining proliferative and differentiation capacity many years after transplantation

Acta Neuropathol. 2016 Apr;131(4):639-40. doi: 10.1007/s00401-016-1543-3. Epub 2016 Feb 2.

Authors

Kevin S Chen¹, Jeremy C McIntyre², Andrew P Lieberman³, Jeffrey R Martens², Parag G Patil⁴

Affiliations

¹ Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Dr., Room 3552 TC, Ann Arbor, MI, 48109-5338, USA. kechen@med.umich.edu.
² Department of Pharmacology and Therapeutics, University of Florida, Gainesville, FL, USA.
³ Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
⁴ Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Dr., Room 3552 TC, Ann Arbor, MI, 48109-5338, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

AC133 Antigen / metabolism
Adult
Cell Differentiation / physiology*
Cell Proliferation / physiology*
Glial Fibrillary Acidic Protein / metabolism
Humans
Keratin-18 / metabolism
Ki-67 Antigen / metabolism
Longitudinal Studies
Membrane Proteins / metabolism
Olfactory Mucosa / cytology
Spinal Cord Diseases / surgery
Stem Cells / physiology*
Transplantation, Autologous*
Young Adult

Substances

AC133 Antigen
CKAP4 protein, human
Glial Fibrillary Acidic Protein
Keratin-18
Ki-67 Antigen
Membrane Proteins

Grants and funding