Zika Virus: Diagnostics for an Emerging Pandemic Threat

Jesse J Waggoner; Benjamin A Pinsky

doi:10.1128/JCM.00279-16

Zika Virus: Diagnostics for an Emerging Pandemic Threat

J Clin Microbiol. 2016 Apr;54(4):860-7. doi: 10.1128/JCM.00279-16. Epub 2016 Feb 17.

Authors

Jesse J Waggoner¹, Benjamin A Pinsky²

Affiliations

¹ Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.
² Department of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA Department of Pathology, Stanford University School of Medicine, Stanford, California, USA bpinsky@stanford.edu.

Abstract

Zika virus (ZIKV) is anAedesmosquito-borne flavivirus that emerged in Brazil in 2015 and then rapidly spread throughout the tropical and subtropical Americas. Based on clinical criteria alone, ZIKV cannot be reliably distinguished from infections with other pathogens that cause an undifferentiated systemic febrile illness, including infections with two common arboviruses, dengue virus and chikungunya virus. This minireview details the methods that are available to diagnose ZIKV infection.

Publication types

Review

MeSH terms

Americas / epidemiology
Clinical Laboratory Techniques / methods*
Diagnostic Tests, Routine / methods*
Humans
Pandemics*
Zika Virus / isolation & purification*
Zika Virus Infection / diagnosis*
Zika Virus Infection / epidemiology*

Grants and funding

K08 AI110528/AI/NIAID NIH HHS/United States