Oral Submucous Fibrosis (SF) which is a relatively unknown disease in the early 60s is now widely regarded as a precancerous condition. In this paper, the author who is associated with the conception of this disease in India would, in addition to sharing his cumulative experience on this subject, review all the literature published since 1967 on Oral Submucous Fibrosis. An attempt is also made to unify current thoughts on the epidemiology, aetiology and clinical significance of this disease.