Zika Virus: Implications for Public Health

Clin Infect Dis. 2016 Jul 15;63(2):227-33. doi: 10.1093/cid/ciw210. Epub 2016 Apr 5.

Abstract

The World Health Organization has declared the current Zika virus (ZIKV) epidemic a public health emergency of international concern. Lack of vaccines and reliable diagnostic tests, broad geographical distribution of mosquito species that can transmit the virus, and absence of population immunity in newly affected countries are causes for concern. Although most infected persons are asymptomatic, ZIKV has been associated with a rise in cases of neurological complications and fetal central nervous system malformations. This defines such an arbovirus as something whose transmission should be prevented. This review summarizes the current understanding of ZIKV biology and epidemiology, as well as possible interventions to prevent contagion and transmission.

Keywords: Aedes aegypti; Aedes albopictus; ZIKAV; Zika virus; microcephaly.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Humans
  • Public Health
  • Zika Virus / physiology*
  • Zika Virus Infection / epidemiology*
  • Zika Virus Infection / prevention & control
  • Zika Virus Infection / transmission