Acute lung function responses to ambient acid aerosol exposures in children

Environ Health Perspect. 1989 Feb:79:179-85. doi: 10.1289/ehp.8979179.

Abstract

We examined the relationship between lung function changes and ambient acid aerosol episodes in children attending a residential summer camp. Young females (112) performed daily spirometry, and 96 were assessed on one occasion for airway hyperresponsiveness using a methacholine bronchoprovocation test. Air quality measurements were performed on site and four distinct acid aerosol episodes were observed during the 41-day study. The maximum values observed during the 41-day study were: O3 at 143 ppb; H2SO4 at 47.7 micrograms/m3; and [H+] at 550 nmole/m3. Maximum decrements of 3.5 and 7% for FEV1 and PEF, respectively, were observed to be associated with the air pollution episodes. There was some evidence of a differential lung function response to the episodes where children with a positive response to a methacholine challenge had larger decrements compared to their nonresponsive counterparts.

MeSH terms

  • Acid Rain / adverse effects*
  • Adolescent
  • Aerosols
  • Air Pollutants / adverse effects*
  • Airway Resistance / drug effects
  • Asthma / etiology*
  • Child
  • Female
  • Humans
  • Lung Volume Measurements*
  • Ozone / adverse effects
  • Particle Size
  • Respiratory Hypersensitivity / etiology*
  • Sulfates / adverse effects
  • Sulfuric Acids / adverse effects

Substances

  • Acid Rain
  • Aerosols
  • Air Pollutants
  • Sulfates
  • Sulfuric Acids
  • Ozone
  • sulfuric acid