SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals

Pablo Carbonell; Andrew Currin; Mark Dunstan; Donal Fellows; Adrian Jervis; Nicholas J W Rattray; Christopher J Robinson; Neil Swainston; Maria Vinaixa; Alan Williams; Cunyu Yan; Perdita Barran; Rainer Breitling; George Guo-Qiang Chen; Jean-Loup Faulon; Carole Goble; Royston Goodacre; Douglas B Kell; Rosalind Le Feuvre; Jason Micklefield; Nigel S Scrutton; Philip Shapira; Eriko Takano; Nicholas J Turner

doi:10.1042/BST20160009

SYNBIOCHEM-a SynBio foundry for the biosynthesis and sustainable production of fine and speciality chemicals

Biochem Soc Trans. 2016 Jun 15;44(3):675-7. doi: 10.1042/BST20160009.

Authors

Pablo Carbonell¹, Andrew Currin¹, Mark Dunstan¹, Donal Fellows¹, Adrian Jervis¹, Nicholas J W Rattray¹, Christopher J Robinson¹, Neil Swainston¹, Maria Vinaixa¹, Alan Williams¹, Cunyu Yan¹, Perdita Barran², Rainer Breitling², George Guo-Qiang Chen², Jean-Loup Faulon², Carole Goble³, Royston Goodacre², Douglas B Kell², Rosalind Le Feuvre⁴, Jason Micklefield², Nigel S Scrutton⁵, Philip Shapira⁶, Eriko Takano⁷, Nicholas J Turner⁷

Affiliations

¹ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K.
² BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM Platform/Theme Lead, School of Chemistry, The University of Manchester, Manchester, U.K.
³ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM Data Lead, School of Computer Science, The University of Manchester, Manchester, U.K.
⁴ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM, Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K.
⁵ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM Platform/Theme Lead, School of Chemistry, The University of Manchester, Manchester, U.K. SYNBIOCHEM, The University of Manchester, Manchester, U.K. nigel.scrutton@manchester.ac.uk.
⁶ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM Responsible Research Innovation Lead, Alliance Manchester Business School, The University of Manchester, Manchester, U.K.
⁷ BBSRC/EPSRC Synthetic Biology Research Centre for Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester, U.K. SYNBIOCHEM Platform/Theme Lead, School of Chemistry, The University of Manchester, Manchester, U.K. SYNBIOCHEM, The University of Manchester, Manchester, U.K.

Abstract

The Manchester Synthetic Biology Research Centre (SYNBIOCHEM) is a foundry for the biosynthesis and sustainable production of fine and speciality chemicals. The Centre's integrated technology platforms provide a unique capability to facilitate predictable engineering of microbial bio-factories for chemicals production. An overview of these capabilities is described.

Keywords: biocatalysis; fine chemicals; metabolic engineering; synthetic biology; systems biology.

MeSH terms

Metabolic Engineering*
Synthetic Biology*
United Kingdom
Universities

Abstract

MeSH terms

Grants and funding